| Course Unit Code | 040-0901/03 |
|---|
| Number of ECTS Credits Allocated | 10 ECTS credits |
|---|
| Type of Course Unit * | Optional |
|---|
| Level of Course Unit * | Third Cycle |
|---|
| Year of Study * | |
|---|
| Semester when the Course Unit is delivered | Winter, Summer Semester |
|---|
| Mode of Delivery | Face-to-face |
|---|
| Language of Instruction | Czech |
|---|
| Prerequisites and Co-Requisites | Course succeeds to compulsory courses of previous semester |
|---|
| Name of Lecturer(s) | Personal ID | Name |
|---|
| DAN40 | prof. RNDr. Pavel Danihelka, CSc. |
| KLO067 | doc. Ing. et Ing. Karel Klouda, CSc., Ph.D.,MBA |
| Summary |
|---|
1. Toxicology as a scientific discipline
2. Basic toxicology terminology
3. Introduction to the management of health risks from toxic substances
4. Hazard identification 1 – the process of hazard identification, classification and labelling of substances and mixtures
5. Hazard identification 2 – toxicity evaluation, information sources on toxic substances
6. Exposure scenarios, assessment of exposure to toxic substances
7. Dose-Response assessment
8. Risk analysis and risk assessment, risk characterization
9. Risk management
10. Management of health risks from professional exposure to toxic substances – case study
11. Summary of legislation – toxic substances and professional exposure to toxic substances
12. Industrial toxicology in the area of major accident prevention
13. Industrial toxicology in the area of fire prevention and protection
14. Reserve
|
| Learning Outcomes of the Course Unit |
|---|
| Student, after the course, understands biological risks in the sense of REACH an CLP Directives, will be able to work with concepts of acute toxicity, corrosivity, irritant properties, carcinogeneity, mutageneity, reproductive toxicity, sensibilization, ecotoxicity. She/he understands the relation dose/effect, the metric of dose under different conditions and will be able to find toxicological data of toxic substances. |
| Course Contents |
|---|
Toxicology as a scientific discipline and management system. Compounds dangerous for human
health and their impacts: system toxicity, cancerogenity, mutageneicity,
reproduction toxicity, teratogenity, corrosivity, irritant properties,
environmental toxicity and other effects (endocrine disruptors, allergens,
sensibilitation). Dose - response dependens, limits of dangerous compouns in
working and living environment, risk assessment, information sources concerning
industrially used chemicals
|
| Recommended or Required Reading |
|---|
| Required Reading: |
|---|
Illing, P. Toxicity and risk. Context, principles and practice. London: Taylor & Francis, 2001, ISBN 0-415-23371-2.
Relative legislation
Databases on toxicology (database system TOXNET) |
- Související legislativa v platném znění (zákon č. 356/2003 Sb., vyhláška č. 232/2004 Sb., nařízení Evropského parlamentu a Rady č. 1907/2006, nařízení Evropského parlamentu a Rady č. 1272/2008 , zákon č. 262/2006 Sb., zákon č. 309/2006 Sb., zákon č. 258/2000 Sb., nařízení vlády č. 361/2007 Sb., vyhláška č. 432/2003 Sb. a další)
- Databázový systém nebezpečných látek TOXNET
- Provazník, K. a kol.: Manuál prevence v lékařské praxi - souborné vydání. Univerzita Karlova: Fortuna, 2004. ISBN 80-7168-942-4
- Tichý, M.: Toxikologie pro chemiky. Toxikologie obecná, speciální, analytická a legislativa. Universita Karlova, Praha, 2002.
- Buchancová, J.: Pracovné lekárstvo a toxikológia. Martin: Osveta, 2003, ISBN: 80-8063-113-1.
- Illing, P. Toxicity and risk. Context, principles and practice. London: Taylor & Francis, 2001, ISBN 0-415-23371-2. |
| Recommended Reading: |
|---|
| Further reading is not required |
| není požadována další literatura |
| Planned learning activities and teaching methods |
|---|
| Lectures, Tutorials |
| Assesment methods and criteria |
|---|
| Tasks are not Defined |