040-0901/02 – Toxicology (TOXI)

Gurantor departmentDepartment of Occupational and Process SafetyCredits10
Subject guarantorprof. RNDr. Pavel Danihelka, CSc.Subject version guarantorprof. RNDr. Pavel Danihelka, CSc.
Study levelpostgraduateRequirementOptional
YearSemesterwinter + summer
Study languageCzech
Year of introduction2004/2005Year of cancellation2010/2011
Intended for the facultiesHGFIntended for study typesDoctoral
Instruction secured by
LoginNameTuitorTeacher giving lectures
DAN40 prof. RNDr. Pavel Danihelka, CSc.
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Examination 20+0
Part-time Examination 20+0

Subject aims expressed by acquired skills and competences

Student, after the course, understands biological risks in the sense of REACH an CLP Directives, will be able to work with concepts of acute toxicity, corrosivity, irritant properties, carcinogeneity, mutageneity, reproductive toxicity, sensibilization, ecotoxicity. She/he understands the relation dose/effect, the metric of dose under different conditions and will be able to find toxicological data of toxic substances.

Teaching methods



1. Toxicology as a scientific discipline 2. Basic toxicology terminology 3. Introduction to the management of health risks from toxic substances 4. Hazard identification 1 – the process of hazard identification, classification and labelling of substances and mixtures 5. Hazard identification 2 – toxicity evaluation, information sources on toxic substances 6. Exposure scenarios, assessment of exposure to toxic substances 7. Dose-Response assessment 8. Risk analysis and risk assessment, risk characterization 9. Risk management 10. Management of health risks from professional exposure to toxic substances – case study 11. Summary of legislation – toxic substances and professional exposure to toxic substances 12. Industrial toxicology in the area of major accident prevention 13. Industrial toxicology in the area of fire prevention and protection 14. Reserve

Compulsory literature:

Illing, P. Toxicity and risk. Context, principles and practice. London: Taylor & Francis, 2001, ISBN 0-415-23371-2. Relative legislation Databases on toxicology (database system TOXNET)

Recommended literature:

Further reading is not required

Way of continuous check of knowledge in the course of semester


Other requirements


Subject has no prerequisities.


Subject has no co-requisities.

Subject syllabus:


Conditions for subject completion

Conditions for completion are defined only for particular subject version and form of study

Occurrence in study plans

Academic yearProgrammeField of studySpec.ZaměřeníFormStudy language Tut. centreYearWSType of duty
2010/2011 (P3904) Engineering Ecology (3904V012) Environment Protection within Industry K Czech Ostrava Optional study plan
2010/2011 (P3904) Engineering Ecology (3904V012) Environment Protection within Industry P Czech Ostrava Optional study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner