040-0901/03 – Toxicology (TOXI)
| Gurantor department | Department of Occupational and Process Safety | Credits | 10 |
| Subject guarantor | prof. RNDr. Pavel Danihelka, CSc. | Subject version guarantor | prof. RNDr. Pavel Danihelka, CSc. |
| Study level | postgraduate | Requirement | Choice-compulsory |
| Year | | Semester | winter + summer |
| | Study language | Czech |
| Year of introduction | 2013/2014 | Year of cancellation | |
| Intended for the faculties | FBI | Intended for study types | Doctoral |
Subject aims expressed by acquired skills and competences
Student, after the course, understands biological risks in the sense of REACH an CLP Directives, will be able to work with concepts of acute toxicity, corrosivity, irritant properties, carcinogeneity, mutageneity, reproductive toxicity, sensibilization, ecotoxicity. She/he understands the relation dose/effect, the metric of dose under different conditions and will be able to find toxicological data of toxic substances.
Teaching methods
Lectures
Tutorials
Summary
1. Toxicology as a scientific discipline
2. Basic toxicology terminology
3. Introduction to the management of health risks from toxic substances
4. Hazard identification 1 – the process of hazard identification, classification and labelling of substances and mixtures
5. Hazard identification 2 – toxicity evaluation, information sources on toxic substances
6. Exposure scenarios, assessment of exposure to toxic substances
7. Dose-Response assessment
8. Risk analysis and risk assessment, risk characterization
9. Risk management
10. Management of health risks from professional exposure to toxic substances – case study
11. Summary of legislation – toxic substances and professional exposure to toxic substances
12. Industrial toxicology in the area of major accident prevention
13. Industrial toxicology in the area of fire prevention and protection
14. Reserve
Compulsory literature:
Recommended literature:
Further reading is not required
Additional study materials
Way of continuous check of knowledge in the course of semester
seminary
E-learning
Other requirements
no additional requirements
Prerequisities
Subject has no prerequisities.
Co-requisities
Subject has no co-requisities.
Subject syllabus:
Toxicology as a scientific discipline and management system. Compounds dangerous for human
health and their impacts: system toxicity, cancerogenity, mutageneicity,
reproduction toxicity, teratogenity, corrosivity, irritant properties,
environmental toxicity and other effects (endocrine disruptors, allergens,
sensibilitation). Dose - response dependens, limits of dangerous compouns in
working and living environment, risk assessment, information sources concerning
industrially used chemicals
Conditions for subject completion
Occurrence in study plans
Occurrence in special blocks
Assessment of instruction
Předmět neobsahuje žádné hodnocení.