450-4031/04 – Biocybernetics (BKY)

Gurantor departmentDepartment of Cybernetics and Biomedical EngineeringCredits4
Subject guarantordoc. Ing. Martin Augustynek, Ph.D.Subject version guarantordoc. Ing. Martin Augustynek, Ph.D.
Study levelundergraduate or graduate
Study languageEnglish
Year of introduction2019/2020Year of cancellation
Intended for the facultiesFEIIntended for study typesFollow-up Master
Instruction secured by
LoginNameTuitorTeacher giving lectures
AUG011 doc. Ing. Martin Augustynek, Ph.D.
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Graded credit 2+2
Part-time Graded credit 0+16

Subject aims expressed by acquired skills and competences

The student aquired during this course information about the origin of genesis, transformation , evaluation and presevation of information in live systems. As well as modeling and simulation of biological systems. Their study of control method on physiological and pathological terms. The object with its elignment fits into branch of measurements and control techniques in biomedicine. The aquiered knowledge and skill creates the basic knowledge of biomedicine engineering.

Teaching methods

Lectures
Individual consultations
Tutorials
Other activities

Summary

The aim of this object is study principle of genesis, transfer, processing and retention information in vital systems. As well as modeling and simulation of biological systems. Their study of control method on physiological and pathological terms. The basis forms a cell, biological membrans, biothermodynamic and biophysical chemistry. The study of biological systems features is orientaited on neurophysiologie, neurological, respiratory, locomotive and vascular systems, heart action, genetical information, sensoric systems and compensation of organ functions.

Compulsory literature:

[1] Biomedical modeling and simulation on a pc: a workbench. S.l.: Springer, 2012. ISBN 9781461391654. [2] MEURS, Willem van. Modeling and simulation in biomedical engineering: applications in cardiorespiratory physiology. 1. New York: McGraw-Hill, c2011. ISBN 978-0071714457. [3] CHRISTOPOULOS, Arthur. Biomedical applications of computer modeling. Boca Raton: CRC Press, c2001. Pharmacology & toxicology (Boca Raton, Fla.). ISBN 9780849301001. [4] KITTNAR, Otomar a Mikuláš MLČEK. Atlas fyziologických regulací: 329 schémat. Praha: Grada, 2009, 316 s. ISBN 978-80-247-2722-6.

Recommended literature:

Tiefenbach,P: Biocybernetics,Sylabus on WWW pages of department,2002. Penhaker,M: Biocybernetics,Sylabus on WWW pages of department,2002. Samson Wright: Klinická fyziologie Praha 1987. Stefan Silbernagl, Agamemnom Despopoulos: Atlas fyziologie člověka. Praha 1984. Wiliam F. Canong: Přehled lékařské fyziologie. Praha 1976. Hrazdíra, I.: Biofyzika. Praha, Avicenum 1990. Nečas, O.: Biologie. Praha, Avicenum 1982. Dvořák - Maršík - Andrej: Biotermodynamika. Praha, Akademia, 1985. Babloyantz, A.: Molecules, dynamics and life, J.Wiley, New York, 1986. Talbot, S.a.: Systems physiology, J.Wiley, New York 1973.

Way of continuous check of knowledge in the course of semester

Practical exercises in the laboratory. Assesment methods and criteria linked to learning outcomes: Course-unit credit: active participation in seminars, submission of reports. Classified credit: Protocols (40 points, min.20), written test (60 points, min.31). Assesment methods and criteria linked to learning outcomes: Attendance at seminars requires at least 80% of the taught lessons.

E-learning

Other requirements

There are no additional requirements for the student

Prerequisities

Subject has no prerequisities.

Co-requisities

Subject has no co-requisities.

Subject syllabus:

Lectures: 1. Physiological principles. 2. System definition, basic division, basic concepts, feedback, system description, mathematical apparatus. 3. Modeling of biological systems, modeling procedure, Models of static systems, models of dynamic systems, stochastic models of biological systems, basic attributes of systems. 4. Human organism as a system - basic properties of the organism, principles of homeostatic control, control mechanisms, stimuli, structure of the biological system, receptors, homeostatic regulation, thermoregulation 5. Biological membranes. Structure and Functions. Chemical potentials. Conditions of equilibrium in heterogeneous systems. Membrane ion channels. Transporter ion transfer systems via membrane. 6. Neurophysiology - nervous system. Transmission and processing of information in biological systems. The nervous, hormonal and humoral level of their management. 7. Nervous System Structure of the nervous system, possibilities of control at individual levels. Central nervous system. Nerve fiber, replacement scheme, and propellant propagation equation. 8. Heart. Heart activity and importance of control mechanisms under load. The vascular system. The importance of the bloodstream for circulation, the possibilities and the importance of its regulation. 9. Heart Rate Control, Blood Pressure Stabilization 10. Breathing system. Control of the respiratory system. Function of the lung and its regulation in extreme conditions. Breath regulation 11. Motion system. The link between electrical irritation and the mechanical response of the muscle cell. Reflections. 12. Water regulation in the organism, regulation of glycemia, pharmacokinetics 13. Replacement of organ functions. Replacement and support of the function of the internal organs. Replacement of kidney, heart and lung function. 14. Stimulators external and implantable. Laboratory Exercises: 1. Introduction to the theory of ordinary differential equations: ODR I., II. order and their systems, general and particular solutions, Cauchy task and Laplace transformation. 2. The solution of ordinary differential equations in Simulink. Numerical solvers of differential equations in MATLAB environment. 3. Analytical solution and simulation of population models. 4. Pharmacokinetics: one compartment and two compartment model of drug passage. 5. Analysis and simulation of heart rate dependence on physical load. 6. Modeling of kidney function in stabilizing blood pressure. 7. Pulse compartment: model of gas concentration in alveoli and other tissues. 8. Gastric acidity control model. 9. Model of enzyme reaction and membrane potential. 10. Model Baroreflex. 11. Pulse model of blood circulation. 12. Model of glycemic control. 13. Modeling of skeletal muscle contraction. 14. Fundamentals of PDE and their application in biomedical modeling.

Conditions for subject completion

Full-time form (validity from: 2019/2020 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Graded credit Graded credit 100 (100) 51
        Semestrální projekt Semestral project 40  21
        Písemka Written test 60  31
Mandatory attendence parzicipation: Verification of study: One test and Gift-over of semestral work. Conditions for credit: On the semestral work maximum 40 points (minimum 20 points). Test (60 points, min. 31 points) It is required mandatory participation in seminars at least 80% from past lessons.

Show history
Part-time form (validity from: 2019/2020 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Graded credit Graded credit 100 (100) 51
        Semestrální projekt Semestral project 40  21
        Písemka Written test 60  31
Mandatory attendence parzicipation: Verification of study: One test and Gift-over of semestral work. Conditions for credit: On the semestral work maximum 40 points (minimum 20 points). Test (60 points, min. 31 points) It is required mandatory participation in seminars at least 80% from past lessons.

Show history

Occurrence in study plans

Academic yearProgrammeField of studySpec.ZaměřeníFormStudy language Tut. centreYearWSType of duty
2022/2023 (N0988A060002) Biomedical Engineering K English Ostrava 2 Choice-compulsory type B study plan
2022/2023 (N0988A060002) Biomedical Engineering P English Ostrava 2 Choice-compulsory type B study plan
2021/2022 (N0988A060002) Biomedical Engineering P English Ostrava 2 Choice-compulsory type B study plan
2021/2022 (N0988A060002) Biomedical Engineering K English Ostrava 2 Choice-compulsory type B study plan
2020/2021 (N0988A060002) Biomedical Engineering P English Ostrava 2 Choice-compulsory type B study plan
2020/2021 (N0988A060002) Biomedical Engineering K English Ostrava 2 Choice-compulsory type B study plan
2019/2020 (N0988A060002) Biomedical Engineering P English Ostrava 2 Choice-compulsory type B study plan
2019/2020 (N0988A060002) Biomedical Engineering K English Ostrava 2 Choice-compulsory type B study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner
V - ECTS - mgr. 2022/2023 Full-time English Optional 401 - Study Office stu. block
V - ECTS - mgr. 2021/2022 Full-time English Optional 401 - Study Office stu. block