546-0332/02 – Toxicology (Toxi)

Gurantor departmentDepartment of Environmental EngineeringCredits5
Subject guarantordoc. Mgr. Eva Pertile, Ph.D.Subject version guarantordoc. Mgr. Eva Pertile, Ph.D.
Study levelundergraduate or graduateRequirementCompulsory
Year3Semesterwinter
Study languageCzech
Year of introduction2007/2008Year of cancellation2016/2017
Intended for the facultiesHGFIntended for study typesBachelor
Instruction secured by
LoginNameTuitorTeacher giving lectures
PER34 doc. Mgr. Eva Pertile, Ph.D.
VAS0028 Ing. Michal Vaštyl, Ph.D.
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Credit and Examination 2+2
Combined Credit and Examination 6+6

Subject aims expressed by acquired skills and competences

The objective of this course is to get a an overview on basic toxicology. After completing this course the student orients in basics of general and experimental toxicology, knows toxic effects of selected substances, including their mechanism of action and the possibility of reducing the risk and consequences of intoxication.

Teaching methods

Lectures
Project work
Other activities

Summary

Interaction of pollutants with living organisms, biotransformation of xenobiotics. Summary of toxicology of inorganic and organic substances. Ecotoxicological testing and evaluation of substances and wastes. Legislation on chemicals and hazardous wastes. Classification and registration of chemical substances and preparations under EU and CR. Sources of toxicological and ecotoxicological information.

Compulsory literature:

WALKER, C.H., Principles of ecotoxicology, Ed. Taylor and Francis, London, 2001.

Recommended literature:

ECOBICHON, J. D.: The Basis of Toxicity Trstiny, CRC Press, Boca Raton 1997. STONE, T., DARLINGTON G.: Pills, Potions and Poisons, Oxford University Press, 2000.

Way of continuous check of knowledge in the course of semester

Consultations within the range of lectures for students of the combined form of study.

E-learning

Další požadavky na studenta

Active participation in lectures and seminars.

Prerequisities

Subject has no prerequisities.

Co-requisities

Subject has no co-requisities.

Subject syllabus:

1. The current concept of toxicology, history, toxicology classification , characteristics of branches. The concept of toxicology in a broader context of science, the definition of basic terms, history. 2. Definition of terms. Toxic material and toxicity. Toxic effects (characteristics, formulations). Poison classification and their effects on organisms. Exposition. 3. Dose (the dose-effect relation). Interaction between toxic matters. Factors influencing toxic effect. 4. Methods of determining the toxicity of substances, biotransformation conversion. Biotransformation (principle, phase, factors affecting biotransformation). 5. Toxocinetics - interaction of a toxic substance with an organism (primary contact, absorption, distribution and transport of toxic substances in the body, excretion). 6. Toxicology at the level of molecules and cells. The mechanism of penetration of toxic substances through biomembranes. Effects of pollutants at the organ level (mechanism, effects, examples of substances). 7. Mutagenesis, carcinogenesis, reproductive and developmental toxicity. Methods for determining the level of exposure, exposure limits. 8. Significant inorganic pollutants and their effects on the body. Basic risk characteristics and toxicological properties of elements and inorganic compounds. 9. Significant organic pollutants and their effects. Basic risk characteristics and toxicological properties of organic compounds. 10. Safety in chemistry, law, information sources. Risks of working with poisons, flammable and explosive substances. 11. Disposal of chemical waste in the laboratory. Legislative regulations and documents defining the handling with chemicals, labour safety. Familiarization with information systems and resources in toxicology. 12. First aid for injuries and poisonings in the laboratory. 13. Current environmental issues.

Conditions for subject completion

Full-time form (validity from: 2010/2011 Winter semester, validity until: 2012/2013 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Exercises evaluation and Examination Credit and Examination 100  51
        Exercises evaluation Credit  
        Examination Examination  
Mandatory attendence parzicipation:

Show history

Occurrence in study plans

Academic yearProgrammeField of studySpec.FormStudy language Tut. centreYearWSType of duty
2015/2016 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2015/2016 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2014/2015 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2014/2015 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2014/2015 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2014/2015 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2013/2014 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2013/2014 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2013/2014 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2013/2014 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2012/2013 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2012/2013 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2012/2013 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2012/2013 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2011/2012 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2011/2012 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2011/2012 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2011/2012 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2010/2011 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering P Czech Ostrava 3 Compulsory study plan
2010/2011 (B2102) Mineral Raw Materials (3904R005) Environmental Engineering K Czech Ostrava 3 Compulsory study plan
2010/2011 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2010/2011 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2009/2010 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2009/2010 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2008/2009 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2008/2009 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan
2007/2008 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Ostrava 2 Compulsory study plan
2007/2008 (B2102) Mineral Raw Materials (3904R022) Waste Treatment and Disposal K Czech Most 2 Compulsory study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner
ECTS - FMG 2016/2017 Full-time English Optional 501 - Study Office stu. block
O - ECTS FMG 2015/2016 Full-time Czech Optional 501 - Study Office stu. block
O - ECTS FMG - Bc. 2014/2015 Full-time Czech Optional 501 - Study Office stu. block
O - ECTS FMG - Bc. 2013/2014 Full-time Czech Optional 501 - Study Office stu. block
O - ECTS FMG - Bc. 2012/2013 Full-time Czech Optional 501 - Study Office stu. block