615-0806/01 – Industrial Toxicology (Tox)

Gurantor departmentDepartment of Analytic Chemistry ProcessesCredits3
Subject guarantorprof. Ing. Petr Praus, Ph.D.Subject version guarantorprof. Ing. Petr Praus, Ph.D.
Study levelundergraduate or graduateRequirementChoice-compulsory
Year1Semesterwinter
Study languageCzech
Year of introduction2004/2005Year of cancellation2013/2014
Intended for the facultiesFMTIntended for study typesFollow-up Master
Instruction secured by
LoginNameTuitorTeacher giving lectures
PAV57 Ing. Jiří Pavlovský, Ph.D.
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Credit and Examination 2+0

Subject aims expressed by acquired skills and competences

Course objectiv is submit complete information about the harmful and toxic effects of substances (organic and inorganic), basic concepts of the toxicity, teratogenity, mutagenity, etc. Subject matter is also focused on the toxicity of fungi, plants, animals, drugs, chemical weapons. Aspects of conversion of toxic substances are explained as in the humans body with the individual processes. Part of course is also the legal site and toxicology valid norms, regulations, laws and regulations by the EU. Special attention is devoted to issue of Ecotoxicology and test according to OECD.

Teaching methods

Lectures
Tutorials

Summary

The subject introduces students to the harmful with effects of chemicals and chemical products for humans (inorganic and organic compounds), the forms of entry of these substances in the body and more detailed metabolism. The subject also focuses on some areas of biochemistry, organic chemistry and biology in relation to toxicology, including first aid in case of involvement with these substances. Part of this subject is devoted to actions which take place in the human body, detailed procedures for removal of toxic substances, their effect on mutation, degeneration, carcinogenity, reproduction, mutagenity, as well as the influence of toxicity on the brain, liver, heart and other organs, etc., which breaks down toxic substances, including acute toxicity tests. Part of the subject is closely oriented on a more detailed interpretation on field that is devoted to molds and the associated toxic effects, including issues related to toxic mushrooms, drugs, medications and warfare substances, including toxicology of plants. Further the subject introduces students to the applicable laws and associated regulations and regulations from the field of chemicals and chemical products, namely the existing bylaws Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 (Text with EEA relevance) and the Law No. 356/2003 Coll., respectively the Law No. 345/2005 Coll., the law on waste, accidents, narcotics and psychotropic substances, etc. Another form are information on the utilization the application of knowledge in chemistry, eventually in other fields, what mean keeping records of chemicals, work and handling with these agents, provided first aid, safety issues, work with chemicals, etc.

Compulsory literature:

[1] Tichý, M.(1998): Toxikologie pro chemiky, Karolinum UK Praha, 90 s [2] Marhold J.: Přehled průmyslové toxikologie. a) Anorganické látky. Avicenum, Praha 1980. b) Organické látky. Avicenum, Praha 1986.

Recommended literature:

[1]. Lazarev N.V.: Chemické jedy v průmyslu. Díl I - Organické látky. Díl II-Anorganické a organické sloučeniny prvků. SZdN, Praha 1959. [2]. Hodgson, E., Levi P.E.: A Textbook of Modern Toxicology. Elsevier Sci. Publ., New York, Amsterdam, London, 1987. [3]. Timbrell, J.A.: Introduction to Toxicology. The 2nd Edition. Taylor and Francis, London, 1994. [4]. Matrka, M., Rustek, V.(1991): Průmyslová toxikologie, VŠCHT Pardubice, 157 s. [5]. Zákon č. 356/2003 Sb. o chemických látkách a chemických přípravcích a o změně některých dalších zákonů. [6]. Zákon č. 362/2004 Sb. o návykových látkách a o změně některých dalších zákonů. [7] Corrigendum to Regulation (EC) No. 1272/2008 of the European Parlament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No. 1907/2006 http://eur-lex.europa.eu/Result.do?T1=V1&T2=2008&T3=1272&RechType=RECH_naturel&Submit=Search.

Way of continuous check of knowledge in the course of semester

E-learning

Další požadavky na studenta

There are no additional requirements for students.

Prerequisities

Subject has no prerequisities.

Co-requisities

Subject has no co-requisities.

Subject syllabus:

- Complete information about the harmful and toxic effects of substances (organic and inorganic) - Basic concepts- toxicity, teratogenity, mutagenity, etc. - Toxicity of fungi, plants, animals, drugs, chemical weapons - Aspects of conversion of toxic substances in the humans body with the individual processes - Legal site of toxicology, valid norms, regulations, laws and regulations by the EU - Special attention of ecotoxicology and tests according to OECD

Conditions for subject completion

Full-time form (validity from: 1960/1961 Summer semester, validity until: 2008/2009 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Exercises evaluation and Examination Credit and Examination 100 (145) 51
        Examination Examination 100  0
        Exercises evaluation Credit 45  0
Mandatory attendence parzicipation:

Show history

Occurrence in study plans

Academic yearProgrammeField of studySpec.FormStudy language Tut. centreYearWSType of duty
2013/2014 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2012/2013 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2011/2012 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2010/2011 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2009/2010 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2008/2009 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2007/2008 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2006/2007 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan
2005/2006 (N3909) Process Engineering (3911T008) Chemical and Physical Methods of Material Testing P Czech Ostrava 1 Choice-compulsory study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner