617-0005/04 – Organic Chemistry (CHO)
Gurantor department | Department of Chemistry | Credits | 6 |
Subject guarantor | doc. Ing. Petr Pánek, CSc. | Subject version guarantor | prof. Ing. Václav Roubíček, CSc.,Dr.h.c. |
Study level | undergraduate or graduate | Requirement | Compulsory |
Year | 1 | Semester | summer |
| | Study language | Czech |
Year of introduction | 2003/2004 | Year of cancellation | 2009/2010 |
Intended for the faculties | FBI | Intended for study types | Bachelor |
Subject aims expressed by acquired skills and competences
The topic of our approach is to emphasize the relationship between structure and reactivity of the most important groups of organic compounds.
Regular lectures are in Czech language, individual consulting and examination may be taken in English.
Teaching methods
Lectures
Seminars
Experimental work in labs
Summary
In fourteen lectures from Organic chemistry is discussed structure and reactivity of saturated, unsaturated aliphatic and alicyclic hydrocarbons, aromatic hydrocarbons and their functional derivatives: derivatives of halogens, derivatives of nitrogen, derivatives of sulfure, derivatives of oxygen (alcohols, phenols, ethers, carbonyl compounds, carboxylic acids and derivatives of carboxylic acids).
Compulsory literature:
Recommended literature:
Way of continuous check of knowledge in the course of semester
E-learning
Other requirements
Prerequisities
Co-requisities
Subject has no co-requisities.
Subject syllabus:
1. Introduction to the Organic Chemistry. Binding properties of carbon atom (molecular orbitals, sigma- and pi- bonds, bond energy, bond polarity, hybridization, electron effects).Principles of the stereochemistry of organic compounds and writting structures (types of formulas and models). Polymerism and isomerism (constitutional- and stereo-isomers, chirality). Conformation.
2.The system and the nomenclature of organic chemistry. Organic compounds classification. Principles of the IUPAC nomenclature.
3.Intermolecular forces. The relationship between the structure and the properties of substances (boiling and melting points, solubility).
4.Reactions of organic compounds and their mechanism. Classifying Organic Chemical Reactions.
Homolysis and heterolysis of bonds to carbon. Radical, electrophilic and nucleophilic species. Molecularity, order and mechanism of the reaction. Reaction energetics and the theory of transition state (energy of activation, free-energy diagrams, reaction heat).
5.Alifatic and alicyclic saturated hydrocarbons.Radical substitution. Cracking (noncatalysed and catalyzed) and isomerisation. Hydrocarbon resources and their utilization. Unsaturated hydrocarbons. Radical and ion additions to multiplebonds. Elimination reactions. Resources and industrial utilization of unsaturated hydrocarbons.
6.Aromatic hydrocarbons. Theory of the aromaticity. Reactions of aromatic compounds (nitration, sulfonation, alkylation, acylation, oxidation, catalytic hydrogenation). Petrochemical and coal-tar sources of aromatic hydrocarbons. Industrial utilization. Polycyclic aromatic hydrocarbons and their toxicological risk.
7. Derivatives of hydrocarbons. Halogen and hydroxy derivatives. Ethers. Properties, toxicology, applications. The most important reactions.
8.Nitrogen derivatives (nitro compounds, amines, nitrogen containing heterocycles). Reactivity, properties, toxicology.
9.Carbonyl compounds. Reactivity ( oxidation, reduction and addition to carbonyl group). Preparation and utilization.
10.Carboxylic acids and their derivatives. Acidity versus structure, neutralization. Reactivity of the carboxylic group (esterification, decarboxylation). Industrially the most important acids and their utilization.
11. Substitution derivatives of carboxylic acids.Halogen and hydroxy acids. Lactones.Amino acids. Lactams. Reactivity, properties, application.
12. Functional derivatives of acids. Acyl halides. Anhydride. Esters. Amides. Nitriles.Reactivity, properties, toxicology, applications. Synthesis and applications.Derivatives of the carbonic acid (phosgene, urea and their sulfur analogues).
Conditions for subject completion
Occurrence in study plans
Occurrence in special blocks
Assessment of instruction
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