617-0404/01 – Organic and Macromolecular Chemistry (OMCH)
| Gurantor department | Department of Chemistry | Credits | 7 |
| Subject guarantor | doc. Ing. Petr Pánek, CSc. | Subject version guarantor | doc. Ing. Petr Pánek, CSc. |
| Study level | undergraduate or graduate | Requirement | Compulsory |
| Year | 3 | Semester | winter |
| | Study language | Czech |
| Year of introduction | 2004/2005 | Year of cancellation | 2016/2017 |
| Intended for the faculties | FMT | Intended for study types | Bachelor |
Subject aims expressed by acquired skills and competences
Providing the knowledge needed to understand principles of the organic chemistry, including problematic aspects of organic macromolecular compounds. Acquisition of the practical experience with basic operations in the preparation, purification and identification of organic compounds in the laboratory.
Teaching methods
Lectures
Experimental work in labs
Summary
After recapitulation of basic fundamentals of general chemistry is attention paid to stucture of organic compounds, basic types of organic ractions and relationship between structure and reactivity. Subsequently are chapters organized so that they combines the most useful features of the traditional functional group approach with one based on reaction mechanisms. Philosophy is to ephasize mechanisms and their common aspect as often as posible, and at the same time to use unifying features of functional groups as the basis for most chapters.
Compulsory literature:
[1] W. H. Brown: Organic Chemistry (Saunders College Publishing, 1995)
[2] W. H. Brown: Organic Polymer Chemistry: (Saunders College Publishing, 1995)
Recommended literature:
[1] Solomons, T. W. G., Fryhle, C. B.: Organic Chemistry (John Wiley & Sons, New York, Chichester, Weinheim 2000)
Additional study materials
Way of continuous check of knowledge in the course of semester
During the term, the knowledge of students will be checked by two written tests. The optional tests of 45 min. duration each will be organized inside laboratories and their results will form a part of final evaluation.
E-learning
Other requirements
There are no additional requirements for students.
Prerequisities
Subject has no prerequisities.
Co-requisities
Subject has no co-requisities.
Subject syllabus:
1.Theoretical basis of organic chemistry, bonding properties of carbon, structure theory, theory of chemical bonds. Types of bonds, inductive and mesomeric effects; types of formulas, models and 3D presentations. Nomenclature of Organic Chemistry.
2.The structure of organic compounds, the shape of molecules, types of isomerism, conformery, absolute and relative configuration. Interactions between molecules and physicochemical properties of organic compounds.
3.Organic reactions. Thermodynamics, kinetics and mechanisms of organic reactions. Cleavage of bonds, types of agents. Bröndsted and Lewis theories of acids and bases, the relationship between structure and acidity, respectively basicity.Oxidation and reduction reactions in organic chemistry.
4.Alkanes and cycloalkanes, their physical and physiological characteristics, methods of
acquisition, chemical properties and reactivity, substitution reaction of radicals (SR), cracking. Alkenes and polyenes, methods of obtaining, isomerism, chemical properties, electrophilic and radical adition (AE, AR), hydrogenation, polymerization, allylic substitution. Alkynes, their physical properties, methods of synthesis and reactivity.
5.Arenes. Aromatic state. Aromatic hydrocarbons, their reactivity, electrophilic aromatic substitution (SEAR), nucleophilic aromatic substitution (SNARE). Polyaromatic and their toxicity.
6. Halogen derivatives of aliphatic and aromatic hydrocarbons, methods of synthesis, properties and reactivity, nucleophilic substitution (SN1, SN2), elimination reactions (E1, E2). Organometallic compounds, preparation and utilization.
7. Alcohols and phenols, ethers and their sulfur analogues , methods of synthesis,
reactivity, utilization.
8. Nitrogen derivatives - amines, azo compounds, diazo compounds, nitro and nitroso compounds and oximes, their properties and reactivity.
9.Carbonyl compounds - aldehydes and ketones, their properties and reactivity, nucleophilic addition to a polarized multiple bond, the reaction of enolat ionts. Dicarbonyl and unsaturated carbonyl compounds.
10.Carboxylic acids and their functional and substitution function derivatives, properties and reactivity.
11,Basic heterocyclic compounds and their reactivity. Five-and six-membered heterocycles derived from oxygen, nitrogen and sulfur. Terminology.
12. Basic chemistry of macromolecular compounds, polymer types and structure, utilization of the technological most important groups of polymers.
13.Methods of the studying organic compounds. Sources of the industrial organic chemistry. Petrochemistry and chemistry of coal tar and pitch. The importance of organic chemistry for the modern human society.
Laboratory:
1. Laboratory syfety guidelines. Basic laboratory techniques.
2. Product identification (boiling and melting point, index of refraction, TLC, IR spectroscopy)
3.-12. Important classis of reactions.
Conditions for subject completion
Occurrence in study plans
Occurrence in special blocks
Assessment of instruction