619-0920/01 – Toxicology of Nanomaterials (TNM)
| Gurantor department | Department of Physical Chemistry and Theory of Technological Processes | Credits | 10 |
| Subject guarantor | Prof. Mgr. Jana Kukutschová, Ph.D. | Subject version guarantor | Prof. Mgr. Jana Kukutschová, Ph.D. |
| Study level | postgraduate | Requirement | Choice-compulsory type B |
| Year | | Semester | winter + summer |
| | Study language | Czech |
| Year of introduction | 2019/2020 | Year of cancellation | |
| Intended for the faculties | HGF, FMT | Intended for study types | Doctoral |
Subject aims expressed by acquired skills and competences
Students will be introduced to toxicology of nanomaterials including significant properties of various types of nanomaterials of synthetic and natural origin and nanomaterials originating unintentionally as by-products of anthropogenic activities and sources emitting nanomaterials to single part of the environment. Students will be able to define potential interactions of nanomaterials with living systems on molecular, cellular and organ levels and describe toxic character of selected nanomaterials including basic methods of toxicity testing.
Teaching methods
Individual consultations
Summary
The subject is focused on deepening student's understanding in the field of biological effects of nanomaterials, physical-chemical parameters of nanomaterials which has impact on biological effects. The subject provides comprehensive overview on experimental methods for toxicity testing of nanomaterials, including methods for characterization of nanomaterials needed for interpretation of biotesting. The aspect of legislative frame related to usage and regulation of nanomaterials is included as well.
Compulsory literature:
A. Dhawan, D. Anderson, R. Shanker: Nanotoxicology: Experimental and Computational Perspectives (Issues in Toxicology), Royal Society of Chemistry 2017.
J. Wegener: Measuring Biological Impacts of Nanomaterials, Springer 2016.
C. Fazarro, D.E. Trybula, W. Tate, J. Hanks: Nanosafety, De Gruyter 2017.
Recommended literature:
Research articles in scientific journals.
Prerequisities
Way of continuous check of knowledge in the course of semester
Zkouška písemná a ústní.
E-learning
Other requirements
No other activities are required.
Prerequisities
Subject has no prerequisities.
Co-requisities
Subject has no co-requisities.
Subject syllabus:
Outline
Definition on classification of nanomaterials
Toxicologically significant parameters of nanomaterials and suitable experimental methods
Effects of nanomaterials on molecular level
Effects of nanomaterials on cellular level
Effects of nanomaterials on tissue and organ level
In vitro toxicity assessment
In vivo toxicity assessment
In silico toxicity assessment
Environmental effects of nanomaterials (examples of single nanomaterials)
Health effects of nanomaterials (examples of case studies)
Legislative frame of nanomaterials regulation
Conditions for subject completion
Occurrence in study plans
Occurrence in special blocks
Assessment of instruction
Předmět neobsahuje žádné hodnocení.