651-0920/01 – Toxicology of Nanomaterials (TNM)

Gurantor departmentDepartment of Chemistry and Physico-Chemical ProcessesCredits10
Subject guarantorProf. Mgr. Jana Kukutschová, Ph.D.Subject version guarantorProf. Mgr. Jana Kukutschová, Ph.D.
Study levelpostgraduateRequirementChoice-compulsory type B
YearSemesterwinter + summer
Study languageCzech
Year of introduction2022/2023Year of cancellation
Intended for the facultiesHGF, FMTIntended for study typesDoctoral
Instruction secured by
LoginNameTuitorTeacher giving lectures
LES05 Prof. Mgr. Jana Kukutschová, Ph.D.
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Examination 20+0
Part-time Examination 20+0

Subject aims expressed by acquired skills and competences

Students will be introduced to toxicology of nanomaterials including significant properties of various types of nanomaterials of synthetic and natural origin and nanomaterials originating unintentionally as by-products of anthropogenic activities and sources emitting nanomaterials to single part of the environment. Students will be able to define potential interactions of nanomaterials with living systems on molecular, cellular and organ levels and describe toxic character of selected nanomaterials including basic methods of toxicity testing.

Teaching methods

Individual consultations


The subject is focused on deepening student's understanding in the field of biological effects of nanomaterials, physical-chemical parameters of nanomaterials which has impact on biological effects. The subject provides comprehensive overview on experimental methods for toxicity testing of nanomaterials, including methods for characterization of nanomaterials needed for interpretation of biotesting. The aspect of legislative frame related to usage and regulation of nanomaterials is included as well.

Compulsory literature:

A. Dhawan, D. Anderson, R. Shanker: Nanotoxicology: Experimental and Computational Perspectives (Issues in Toxicology), Royal Society of Chemistry 2017. J. Wegener: Measuring Biological Impacts of Nanomaterials, Springer 2016. C. Fazarro, D.E. Trybula, W. Tate, J. Hanks: Nanosafety, De Gruyter 2017.

Recommended literature:

Research articles in scientific journals. Prerequisities

Way of continuous check of knowledge in the course of semester

Zkouška písemná a ústní.


Other requirements

No other activities are required.


Subject has no prerequisities.


Subject has no co-requisities.

Subject syllabus:

Outline Definition on classification of nanomaterials Toxicologically significant parameters of nanomaterials and suitable experimental methods Effects of nanomaterials on molecular level Effects of nanomaterials on cellular level Effects of nanomaterials on tissue and organ level In vitro toxicity assessment In vivo toxicity assessment In silico toxicity assessment Environmental effects of nanomaterials (examples of single nanomaterials) Health effects of nanomaterials (examples of case studies) Legislative frame of nanomaterials regulation

Conditions for subject completion

Part-time form (validity from: 2022/2023 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Examination Examination  
Mandatory attendence parzicipation:

Show history

Occurrence in study plans

Academic yearProgrammeField of studySpec.ZaměřeníFormStudy language Tut. centreYearWSType of duty
2022/2023 (P0719D270002) Nanotechnology K Czech Ostrava Choice-compulsory type B study plan
2022/2023 (P0719D270002) Nanotechnology P Czech Ostrava Choice-compulsory type B study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner