651-3331/01 – Environmental and health aspects of nanomaterials (EZAN)
| Gurantor department | Department of Chemistry and Physico-Chemical Processes | Credits | 4 |
| Subject guarantor | Prof. Mgr. Jana Kukutschová, Ph.D. | Subject version guarantor | Prof. Mgr. Jana Kukutschová, Ph.D. |
| Study level | undergraduate or graduate | Requirement | Choice-compulsory type B |
| Year | 2 | Semester | summer |
| | Study language | Czech |
| Year of introduction | 2023/2024 | Year of cancellation | |
| Intended for the faculties | FMT | Intended for study types | Follow-up Master |
Subject aims expressed by acquired skills and competences
Student achieves an overview of potential impacts of engineered nanomaterials and also of those originating as by-products of anthropogenic activities, on single components of the environment and human health. Student is able to explain potential transport routes of nanomaterials, their (bio)transformation and (bio)accumulation within their environmental fate. Graduate of the subject is able to discuss single aspects of air, water and soil pollution related to selected nanomaterials. Student is able to describe in general terms potential adverse effects of nanomaterials on living organisms on molecular, cellular and organ level and to describe health impact related to single types of exposure. With respect to nanomaterials usage and their impact, student is able to outline potential ethical issues of these applications, their toxicity assessment and also to describe legislation framework of this topic.
Teaching methods
Lectures
Tutorials
Summary
Předmět je komplexně zaměřen na problematiku uvolňování, přeměn a možných dopadů přítomnosti nanomateriálů v jednotlivých složkách životního prostředí. Probírána je problematika kontaminace jednotlivých složek životního prostředí nanomateriály a možné dopady z toho vyplývající, včetně konečné fáze životního cyklu nanomateriálů, kdy se z nich stávají odpadní materiály. V důsledku expozice živých organismů těmto materiálům v prostředí je pozornost věnována možným účinkům nanomateriálů na živé organismy na úrovni molekulové, buněčné a orgánové a to pro organismy různých trofických úrovní. S ohledem na problematiku testování nanomateriálů jsou součástí náplně předmětu také etické aspekty a v konečné fázi také legislativní rámec používání nanomateriálů.
Compulsory literature:
Recommended literature:
1. Publications in scientific journals.
Way of continuous check of knowledge in the course of semester
Seminar work and presentation of the selected topic within the group.
E-learning
Other requirements
There are no other requirements.
Prerequisities
Subject has no prerequisities.
Co-requisities
Subject has no co-requisities.
Subject syllabus:
1. Introduction – potentially hazardous properties of nanomaterials.
2. Occurence of nanomaterials in the environment – their origin and sources emitting nanomaterials. Indoor and workplace nanomaterials.
3. Environmental risks – air, water and soil pollution – case studies.
4. Environmental fate of nanomaterials in single coponents of the environment.
5. Life cycle assessment (LCA). Nanomaterials as wastes.
6. Exposure to nanomaterials – exposure measurements, nanomaterials intake by organisms, cellular intake, translocation within an organism, biotransformation, bioaccumulation, deposition in single parts of an organism.
7. Types of interaction with biosystems on molecular and cellular level.
8. Impact of nanomaterials on tissue and organ levels. Genotoxic effects, oxidative stress.
9. In vitro and in vivo toxicity assessment of nanomaterials.
10. Ekotoxicity of nanomaterials.
11. Inhalation toxicity – case study.
12. Health impact of nanomaterials, occupational safety.
13. Safe by design strategies in design and development of nanomaterials. Ekofriendly alternatives of selected nanomaterials.
14. Ethical aspects of nanomaterials usage. Legislative framework of nanomaterials usage.
Conditions for subject completion
Occurrence in study plans
Occurrence in special blocks
Assessment of instruction
Předmět neobsahuje žádné hodnocení.