9360-0128/01 – Basics of Toxicology (TOX)

Gurantor departmentCNT - Nanotechnology CentreCredits2
Subject guarantorIng. Zdenek LacnýSubject version guarantorIng. Zdenek Lacný
Study levelundergraduate or graduateRequirementCompulsory
Study languageCzech
Year of introduction2019/2020Year of cancellation
Intended for the facultiesFMTIntended for study typesBachelor
Instruction secured by
LoginNameTuitorTeacher giving lectures
LAC10 Ing. Zdenek Lacný
Extent of instruction for forms of study
Form of studyWay of compl.Extent
Full-time Examination 2+0

Subject aims expressed by acquired skills and competences

Basic knowledge of toxicology.

Teaching methods



The subject "Basics of Toxicology" serves to familiarize students with basic problems of toxicity of chemical compounds, mechanisms of entry, absorption, distribution, biotransformation and excretion of xenobiotics from the organism. The basic toxicokinetic and toxicodynamic concepts used in the literature are defined. In detail, toxicologically relevant inorganic and organic compounds are discussed. part of the subject is focused on current legislation and basic overview of labor safety rules in chemical laboratory, as well as principles of first aid in intoxication.

Compulsory literature:

J.H. Duffus, H.G.J. Worth.: Fundamental Toxicology for Chemists ,The Royal Society of Chemistry,1996 [ISBN 0854045295] HODGSON, Ernest. A textbook of modern toxicology. 3rd ed. Hoboken: Wiley, 2004. ISBN 0-471-64677-6.

Recommended literature:

Flanagan R. J.: Fundamentals of Analytical Toxicology, J. Wiley 2007, West Sussex. DONALDSON, Kenneth a Paul BORM, ed. Particle toxicology. Boca Raton: CRC Press/Taylor & Francis, c2007. ISBN 978-0-8493-5092-4.

Way of continuous check of knowledge in the course of semester

Exam based on two drawn questions.


Other requirements

Additional requirements for students not exist at this time.


Subject has no prerequisities.


Subject has no co-requisities.

Subject syllabus:

1. Fundamentals of toxikology. 2. Basic terms of toxikology and its history. 3. Toxic effect and characteristic of toxic effect. 4. Relationship between dose and effectRoutes of Human Exposure from the Environment 5. Biotransformation 6. Local and Systemic Effects 7. Acute and Chronic Toxicity 8. Uptake toxic substances by organism 9. Harmful Effects of Some Toxic Substances – inorganic compounds 10. Harmful Effects of Some Toxic Substances – organic compounds 11. Chemical Safety Information 12. Environmental Toxicology 13. Hazard and Risk 14. Management of Potentially Toxic Substances

Conditions for subject completion

Full-time form (validity from: 2019/2020 Winter semester)
Task nameType of taskMax. number of points
(act. for subtasks)
Min. number of points
Examination Examination 100  51
Mandatory attendence parzicipation: 90 %

Show history

Occurrence in study plans

Academic yearProgrammeField of studySpec.ZaměřeníFormStudy language Tut. centreYearWSType of duty
2021/2022 (B0719A270001) Nanotechnology P Czech Ostrava 2 Compulsory study plan
2020/2021 (B0719A270001) Nanotechnology P Czech Ostrava 2 Compulsory study plan
2019/2020 (B0719A270001) Nanotechnology P Czech Ostrava 2 Compulsory study plan

Occurrence in special blocks

Block nameAcademic yearForm of studyStudy language YearWSType of blockBlock owner